Methods and reagents for the identification and regulation of senescence-related genes

Publication Date

April 28, 1998

Patent Number

US5744300A

Abstract

Identification of senescence-related genes can be accomplished by comparing mRNA expression between young and senescent cells. Probes complementary to such genes can be used to detect senescent cells and distinguish between young and senescent cells as well as in screens to identify compounds that alter expression levels of senescence-related genes.